Clinical Efficacy and Safety of Calebin A in Managing Weight: Results from a Randomized, Double-blind, Mono-centric, Placebo controlled study
Objective and Study Design

A Randomized, Double-blind, Mono-centric, Placebo controlled study was conducted to assess the efficacy and safety of Calebin A in managing weight in 40 obese or overweight individuals for 90 days.


Subjects were administered Calebin A capsules (25 mg, one capsule twice a day) or placebo.

  • Significant reduction in body weight and body mass index were observed in the Calebin A group compared with placebo after 90 days
  • Significant change in serum biomarkers like leptin, adiponectin, and cortisol was observed in the study subjects with improved blood lipid profiles (Figure 3)
  • Moreover, Calebin A was found to be safe and well-tolerated by all the subjects

Clinical study showed that Calebin A is effective in managing healthy body weight by inhibiting adipogenesis and is an ideal candidate to support metabolic health.

Figure 3: Health benefits of Calebin A as observed in the clinical study